The NaCoMag Coatings are based on a genetically modified protein with the intrinsic ability to self-assemble on various surfaces in a reproducible, highly stable way. Via genetic engineering various biologically active sites can be introduced into the self-assembling protein cushion allowing for the oriented, dense, reproducible and stable presentation of such active sites in a non-denaturing environment. NaCoMag Coatings presenting novel binding regions of antibodies, peptides, enzymes, etc. can be created within weeks. For example self-assembling nanocoatings with the following integral functionalities have been generated in the past:
- Green Fluorescence Protein (GFP)
- Camel Antibodies
- Gluconase (enzyme)
- Strep-tag
- Protein Azz
- Peptide Binders
Comparison of classic, random protein immobilisation and immobilisation via NaCoMag coating technology – NaCoMag coating results in more active binding sites, increased density and higher reproducibility.